Cantargia AB meddelade idag att en ansökan lämnats in kring en klinisk studie som undersöker antikroppen CAN04 i kombination med FOLFIRINOX för första linjens behandling av metastatisk bukspottkörtelcancer (PDAC). Studien är designad att komplettera det pågående kliniska programmet och därmed bredda utvecklingen av CAN04.

Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP). The antibody CAN04 binds IL1RAP with high affinity and functions through both Antibody-Dependent Cellular Cytotoxicity (ADCC) and blockade of IL-1 signaling.

A First-in-Human Study of CAN04 in Patients With Solid Malignant Tumors (CANFOUR) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Cantargia AB meddelade idag att en ansökan lämnats in kring en klinisk studie som undersöker antikroppen CAN04 i kombination med FOLFIRINOX för första linjens behandling av metastatisk bukspottkörtelcancer (PDAC). Studien är designad att komplettera det pågående kliniska programmet och därmed bredda utvecklingen av CAN04. Cantargia AB meddelade idag att en ansökan lämnats in kring en klinisk studie som undersöker antikroppen CAN04 i kombination med FOLFIRINOX för första linjens behandling av metastatisk bukspottkörtelcancer (PDAC). Studien är designad att komplettera det pågående kliniska programmet och därmed bredda utvecklingen av CAN04.

Cantargia can04

15.94. +0.06. +0.38%. MARKET CAP. 1.2B Cantargia: CAN04 ASCO 2019 presentation.

Antikroppen CAN04 binder IL1RAP 10 Mar 2021 Cantargia AB today announced the submission of a clinical trial application investigating antibody CAN04 in combination with FOLFIRINOX for 23 Aug 2019 The investigational antibody CAN04 binds IL1RAP with high affinity and functions through both ADCC and blockade of interleukin 1 signaling. 27 Nov 2020 BioInvent and Cantargia have signed a manufacturing agreement for Apart from CAN10, Cantargia is developing another antibody CAN04, 17 Nov 2015 BRIEF-Cantargia selects two cancer forms as primary indications for CAN04 cancer have been selected as primary indications for CAN04. 19 Mar 2021 Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP).

Cantargia develops antibody-based pharmaceuticals against IL1RAP. The antibody CAN04 binds IL1RAP with high affinity and functions through both Antibody-Dependent Cellular Cytotoxicity (ADCC) and blockade of IL-1 signaling. Preclinical data show that CAN04 increases the efficacy of chemotherapy.

and has just started a Phase IIa clinical trial with its main product, CAN04. 26 May 2019 CAN04 is a first-in-class fully humanized monoclonal antibody targeting IL1RAP blocking IL-1 alpha and beta signaling and triggering antibody 11 Dec 2019 Cantargia's lead product, CAN04 is being tested in the CANFOUR Phase 1/2a clinical trial in people with pancreatic cancer and non-small cell 25 Jan 2019 Cantargia is developing the antibody CAN04 for treatment of cancer. CAN04 is investigated in the CANFOUR phase I/IIa clinical trial.

23 Aug 2019 The investigational antibody CAN04 binds IL1RAP with high affinity and functions through both ADCC and blockade of interleukin 1 signaling.

Cantargia submits IND application for CAN04 Cantargia AB today announced that the application for a US IND regarding the antibody CAN04 has been submitted to the US FDA. 2021-03-10 (R) Cantargia submits application to start new clinical trial investigating antibody CAN04 and FOLFIRINOX in pancreatic can 2021-03-01 Cantargia provides business updates at investor conferences during March 2021 (R) = Regulatory press releases Cantargia develops antibody-based pharmaceuticals against IL1RAP. The antibody CAN04 binds IL1RAP with high affinity and functions through both Antibody-Dependent Cellular Cytotoxicity (ADCC) and blockade of IL-1 signaling. Preclinical data show that CAN04 increases the efficacy of chemotherapy. Cantargia AB today announce new positive preclinical data which defines a novel additional development opportunity for Cantargias antibody CAN04. The molecular target for CAN04, IL1RAP, has been detected on the cancer cells in approximately 80 % of patients with bladder cancer. Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP). The antibody CAN04 binds IL1RAP with high affinity and functions through both Cantargia develops antibody-based pharmaceuticals against IL1RAP.

Cantargia posted a Q1 report that contained few surprises, which we take to be a positive sign that the ph IIa study for the flagship product, CAN04, is progressing according to plan.
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Cantargia AB tillkännagav idag de första interimsresultaten med antikroppen CAN04 i kombination med cellgifter i den pågående fas IIa CANFOUR-studien. Cantargia avancerar utvecklingen av CAN04 genom framgångsrik uppskalning av produktionen fre, feb 14, 2020 12:30 CET. Cantargia AB (publ) tillkännagav idag att bolaget har nått en viktig milstolpe under utvecklingen av sitt antikroppsprojekt CAN04, som är i kliniska fas IIa-studier för cancerbehandling, med den första GMP-produktionen av CAN04 i en volym på 2 000 liter.

Katalysatorer i närtid är utfallet från Novartis fas 3-studie Canopy-1 under andra halvåret 2021 och uppdaterade resultat från Cantargias fas 2a-studie Canfour senare i år. ”Cantargia har lyckats att utföra de flesta kritiska processerna under denna första fas av COVID-19-utbrottet med en minimal påverkan på tidslinjer för utvecklingen. Viktigast av allt är att den initiala doseskaleringsfasen i CANFOUR-studien har avslutats och en dosnivå på 5 mg/kg har valts för kombinationsterapin med CAN04. STOCKHOLM (Nyhetsbyrån Direkt) Forskningsbolaget Cantargias läkemedelskandidat Can04 har ett bredare angreppssätt än Novartis canakinumab (ACZ885) som i studien Canopy-2 inte uppnådde sitt primära mål i fas 3 enligt besked från det schweiziska bolaget på tisdagen.
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Cantargia AB today announced that the IND application regarding the antibody CAN04 has been approved by the US FDA. CAN04, an antibody targeting interleukin 1 receptor accessory protein (IL1RAP), is currently being investigated for treatment of non-small cell lung cancer (NSCLC) and pancreatic cancer (PDAC) in phase IIa clinical development.

Forskningsbolaget Cantargia ansöker om att få starta en tredje parallell studie med antikroppen CAN04, denna gång i kombination med Cantargia develops antibody-based pharmaceuticals against interleukin-1 receptor accessory protein (IL1RAP). The antibody CAN04 binds Cantargia. CANTA. NASDAQ Stockholm.

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2021-03-10 (R) Cantargia submits application to start new clinical trial investigating antibody CAN04 and FOLFIRINOX in pancreatic can 2021-03-01 Cantargia provides business updates at investor conferences during March 2021 (R) = Regulatory press releases

The lead project CAN04 is in phase IIa clinical development for treatment of cancer Detailed Description: CAN04 is a first-in-class fully humanized and ADCC enhanced monoclonal antibody, targeting the Interleukin 1 Receptor Accessory Protein (IL1RAP). The CAN04 strategy is to attack the IL1RAP target molecule using an effective antibody-based cancer treatment. 2021-2-5 · Cantargia reports positive interim data from ongoing phase IIa combination study with antibody CAN04 Mon, Dec 02, 2019 10:30 CET. Cantargia AB today announced the first interim data with antibody CAN04 in combination with chemotherapy in the ongoing phase IIa CANFOUR study. Cantargia AB today announced the submission of a clinical trial application investigating antibody CAN04 in combination with FOLFIRINOX for first line treatment of metastatic pancreatic cancer 2020-5-14 · Cantargia is a Swedish biotechnology company focused on developing new concepts for immunotherapeutic treatment of cancer and autoimmune / inflammatory diseases. Our development program includes the product candidate CAN04, which is in phase IIa of the clinical studies, as well as our development project CAN10. 2021-3-1 · Cantargia AB (publ), reg.